DEMO ONLY — Do not enter real patient information. This prototype is not HIPAA-compliant, does not store data securely, and is not intended for clinical decision-making.

CARE-NFL-PRO-v2.0Draft Research Instrument · Demo Mode

BeaconCR Intelligence Layer Demo

CARE-NFL-PRO-v2.0 demonstrates how BeaconCR can convert structured patient and caregiver outcome responses into domain scores, severity bands, research summaries, trend previews, and machine-readable registry outputs.

0 / 24 items answered · 7-day recall · response scale 0 (none) – 10 (maximum burden)

PRO Analytics Engine

Dynamic questionnaire — 8 domains.

Cognition

Over the past week, how much difficulty with short-term memory?—
Over the past week, how much difficulty sustaining attention or focus?—
Over the past week, how much slowing of thinking or processing speed?—

Neurological Symptoms

Over the past week, how severe were headaches?—
Over the past week, how much dizziness or balance difficulty?—
Over the past week, how much tremor, spasticity, or motor-control difficulty?—

Sleep

Over the past week, how much difficulty falling asleep?—
Over the past week, how much night-time waking?—
Over the past week, how unrefreshing was your sleep?—

Mood / Emotional Health

Over the past week, how much low or depressed mood?—
Over the past week, how much anxiety or worry?—
Over the past week, how much irritability or frustration?—

Functional Status

Over the past week, how much difficulty with daily self-care activities?—
Over the past week, how much difficulty with mobility or walking?—
Over the past week, how much assistance was needed from others?—

Quality of Life

Over the past week, how much were valued activities limited?—
Over the past week, how much was social engagement reduced?—
Over the past week, how reduced was overall sense of wellbeing?—

Caregiver Observations

Over the past week, how much worsening did you observe in the patient?—
Over the past week, how much did care demands increase?—
Over the past week, how much strain did you experience as a caregiver?—

Treatment Response

Since the last visit, how little perceived benefit from current therapy? (0 = strong benefit)—
Over the past week, how much side-effect or tolerability burden?—
Since the last visit, how much have symptoms worsened overall?—

Overall Domain Burden Score

0/10

Domain Burden Analysis

Cognition
0
Neurological Symptoms
0
Sleep
0
Mood / Emotional Health
0
Functional Status
0
Quality of Life
0
Caregiver Observations
0
Treatment Response
0

Research Pattern Detection

v1.0

Research signals — cross-domain, threshold-based. Not diagnostic.

No cross-domain research signals at current thresholds.

Domain Burden Ranking

Answer items to rank domains by reported burden.

Longitudinal Trend Preview

Baseline*Visit 2*Current (live)

* Illustrative prior points for demo. Production uses stored visit history.

AI-Assisted Research Report Preview

Complete the questionnaire to generate a research summary draft.

Drafting aid generated from structured responses — requires review by qualified study personnel before any research use.

Instrument Metadata

Instrument
CARE-NFL-PRO-v2.0
Version
2.0
Status
Draft Research Instrument
Mode
Demo Mode
Domains
8
Recall
7-day recall

Scoring Model

  • Each item scored 0 (none) – 10 (maximum burden).
  • Domain score = mean of answered items in that domain.
  • Overall score = mean of answered domain scores.
  • Severity bands: Mild (0–2.5), Moderate (2.5–5), Severe (5–7.5), Very Severe (7.5–10).
  • Patterns: cross-domain threshold rules (research signals only).

Structured Research JSON Export

{
  "instrument": "CARE-NFL-PRO-v2.0",
  "respondent_type": "caregiver",
  "visit": "baseline",
  "domains": [
    {
      "domain_id": "cognition",
      "domain_label": "Cognition",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_cog_01",
          "subdomain": "memory",
          "response_value": null
        },
        {
          "question_id": "q_cog_02",
          "subdomain": "attention",
          "response_value": null
        },
        {
          "question_id": "q_cog_03",
          "subdomain": "processing",
          "response_value": null
        }
      ]
    },
    {
      "domain_id": "neuro",
      "domain_label": "Neurological Symptoms",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_neu_01",
          "subdomain": "headache",
          "response_value": null
        },
        {
          "question_id": "q_neu_02",
          "subdomain": "balance",
          "response_value": null
        },
        {
          "question_id": "q_neu_03",
          "subdomain": "motor",
          "response_value": null
        }
      ]
    },
    {
      "domain_id": "sleep",
      "domain_label": "Sleep",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_slp_01",
          "subdomain": "onset",
          "response_value": null
        },
        {
          "question_id": "q_slp_02",
          "subdomain": "maintenance",
          "response_value": null
        },
        {
          "question_id": "q_slp_03",
          "subdomain": "quality",
          "response_value": null
        }
      ]
    },
    {
      "domain_id": "mood",
      "domain_label": "Mood / Emotional Health",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_mood_01",
          "subdomain": "depression",
          "response_value": null
        },
        {
          "question_id": "q_mood_02",
          "subdomain": "anxiety",
          "response_value": null
        },
        {
          "question_id": "q_mood_03",
          "subdomain": "irritability",
          "response_value": null
        }
      ]
    },
    {
      "domain_id": "function",
      "domain_label": "Functional Status",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_fun_01",
          "subdomain": "adl",
          "response_value": null
        },
        {
          "question_id": "q_fun_02",
          "subdomain": "mobility",
          "response_value": null
        },
        {
          "question_id": "q_fun_03",
          "subdomain": "independence",
          "response_value": null
        }
      ]
    },
    {
      "domain_id": "qol",
      "domain_label": "Quality of Life",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_qol_01",
          "subdomain": "participation",
          "response_value": null
        },
        {
          "question_id": "q_qol_02",
          "subdomain": "social",
          "response_value": null
        },
        {
          "question_id": "q_qol_03",
          "subdomain": "wellbeing",
          "response_value": null
        }
      ]
    },
    {
      "domain_id": "caregiver",
      "domain_label": "Caregiver Observations",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_cg_01",
          "subdomain": "observed_change",
          "response_value": null
        },
        {
          "question_id": "q_cg_02",
          "subdomain": "care_demand",
          "response_value": null
        },
        {
          "question_id": "q_cg_03",
          "subdomain": "strain",
          "response_value": null
        }
      ]
    },
    {
      "domain_id": "treatment",
      "domain_label": "Treatment Response",
      "score": 0,
      "severity_band": "Mild",
      "questions": [
        {
          "question_id": "q_trt_01",
          "subdomain": "benefit",
          "response_value": null
        },
        {
          "question_id": "q_trt_02",
          "subdomain": "tolerability",
          "response_value": null
        },
        {
          "question_id": "q_trt_03",
          "subdomain": "trajectory",
          "response_value": null
        }
      ]
    }
  ],
  "overall_score": 0,
  "highest_burden_domain": "",
  "pattern_flags": [],
  "generated_summary": "Complete the questionnaire to generate a research summary draft.",
  "timestamp": "2026-06-04T00:00:00Z"
}
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This demo is a research workflow prototype. It is not a validated clinical instrument, diagnostic tool, medical device, treatment recommendation engine, or substitute for clinician judgment. Any real-world implementation requires IRB review, privacy/security controls, validation planning, and appropriate regulatory oversight.